Approximately 1 in 5 women with breast cancer have HER2+ (Human Epidermal growth factor Receptor 2-positive) breast cancer. For women with HER2+ breast cancer, Herceptin (generic name: Trastuzumab) can be used as a form of treatment.

The HER 2 positive breast cancer gene is present in all human cells and is responsible for the division and growth of the cell. But too many HER2 genes in a cell can result in an over-abundance of receptors on the cell’s surface; this is called protein over-expression. Over-expression causes cells to divide uncontrollably, leading to the cancer spreading.

Testing to see whether or not your breast cancer is HER2+ will determine which cancer therapies to pursue. Herceptin is a HER2-targeted therapy. More specifically, it is a HER2-specific antibody that binds to the cancer cells and disrupts the uncontrolled growth cycle. Due to continued positive results, Herceptin has become the first-line therapy for HER2+ breast cancer.

Additionally, Herceptin can be used as a form of continued maintenance therapy for patients’ remission from HER2+ breast cancer. Sequential Herceptin treatments beyond the initial chemotherapy regimen have demonstrated positive results for patients in remission and have contributed to an increased survival rate in women with HER2+ breast cancer.

At Oncology Specialists of Charlotte, we are here to guide you through the complicated decisions you’ll face when you receive a painful diagnosis. If you have been diagnosed with breast cancer and are curious about treatments like Herceptin, don’t hesitate to contact us today.

Request An AppointmentNew patient appointments require a physician to send a referral request on your behalf. The referring physician can be a specialist you saw who identified an oncology-related condition or your primary care physician
  • New patient: you have a medical condition that is or could be cancerous or a blood disorder
  • Transfer care: you are moving into the area and need an oncologist/hematologist, or you are currently under the care of a local oncologist/hematologist and would like to transfer care to one of our physicians
  • 2nd Opinion: you have been diagnosed with cancer or a blood disorder and would like to get a second opinion on the prognosis and treatment course
  • Former patient: if you have not been to the office in 3 years or more, you will need to get a referral sent in by a physician to re-establish care

Send the referral form to your physician to refer and ask them to send with the following items:


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